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Dr Aravinthan Varatharaj

 BMBCh MA(Oxon) PhD PGCME MRCP
Associate Professor in Neurology

Accepting applications from PhD students.

Connect with Aravinthan

Profile photo 
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Name 
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Job title 
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Research interests (for researchers only) 
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In , select ‘Edit profile’. Under the heading 'Curriculum and research description', select 'Add profile information'. In the dropdown menu, select 'Research interests: use separate lines'.

Contact details 
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ORCID ID 
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Accepting PhD applicants (for researchers only) 
Choose to show whether you’re currently accepting PhD applicants or not in . Select ‘Edit profile’. In the 'Portal details' section, select 'Yes' or 'No' to indicate your choice. 

TV

I am a clinical academic neurologist with a subspecialist interest in multiple sclerosis. My clinical practice is based at .

My research interests include:

  • The impact of systemic infection on the brain, in particular how this affects people with neurological diseases. Systemic infections are the for people with neurological disease and are associated with poor outcomes. I am the Chief Investigator of the MRC-funded study which is looking at multiple sclerosis in particular.
  • Blood-brain barrier (BBB) health, and its measurement for research and clinical use with , which I set up in Southampton. BBB disruption may explain how systemic infection and inflammation . This technique can also help guide and I am exploring this in the EQUANIMS study, in collaboration with the at Bournemouth University. In the PEBBAL study we are investigating use in Alzheimer's disease (funded by the ) . Meanwhile in the upcoming SUNLIGHT study I will be testing if we can use this for people with traumatic brain injury (funded by ).
  • Regional differences in cerebral blood vessels, and how this impacts differential susceptibility to disease. I have an interdisciplinary collaboration with Professor Zudi Lu (City University of Hong Kong) and Dr Chao Zheng to investigate this using spatial statistics.
  • Neurological complications of COVID-19. I co-founded the CoroNerve Studies Group which led the for neurological complications of COVID-19. I provide medical advice to about brain injury related to Covid.
  • Clinical trials in multiple sclerosis, and I am currently involved in Southampton's recruitment for , a major new treatment trial for people with progressive MS. I am also the PI for the in Hampshire Hospitals.

 

I am also interested in how medicine, particularly neurology, is represented in literature. I have written on the works of , and , and appeared on BBC Radio 4 discussing . Together with Linda Turner, I teach how the 'Science of Deduction' can be applied to medicine.

I contribute to public understanding of research through work with the .

Nationally, I work with the as part of the MRCP(UK) Specialty Question Writing Group, and sit on the Research Committee.

You can update this in . Select ‘Edit profile’. Under the heading and then ‘Curriculum and research description’, select ‘Add profile information’. In the dropdown menu, select - ‘TV’.

Write about yourself in the third person. Aim for 100 to 150 words covering the main points about who you are and what you currently do. Clear, simple language is best. You can include specialist or technical terms.

You’ll be able to add details about your research, publications, career and academic history to other sections of your staff profile.